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general mycology a brief review

Requirements

  • microiology basics

Description

 

In this course

introduction

history of mycology

Morphology of fungi

Growth of fungi

Metabolism of fungi

Genetics f fungi

Diseases caused by fungi

Allergies

Mycosis

Mycotoxin

Laboratory diagnosis of fungi

Antifungal Drugs used in treatment fungal diseases

 

HISTORY OF THE SCIENCE

The term “mycology” is derived from Greek word “mykes” meaning mushroom.     Therefore mycology is the study of fungi The ability of fungi to invade plant and animal tissue was observed in early 19th century but the first documented animal infection by any fungus was made by Augastino Bassi , who in 1835 studied the muscardine disease of silkworm proved that the infection was caused by a fungus Beauveria bassiana. Remark, who found the fungal nature of favus in 1837 Berg who reported oral candidiasis in 1841 Wilkinson, who described vaginal candidiasis in 1849. Tinea versicolor was described clinically in 1846 by Eichstaedt, and its etiologic agent was identified in 1853. Beigel reported white Piedra in 1856 Piedra, which means “stone” in Spanish, is an asymptomatic superficial fungal infection of the hair shaft. In 1865, Beigel first described Piedra in The Human Hair: Its Structure, Growth, Diseases, and Their Treatment; although, he may have been describing Aspergillus infection. Cerqueira, tinea nigra in 1891 In 1910 Raymond Sabouraud published his book Les Teignes, which was a comprehensive study of dermatophytic fungi. He is also regarded as father of medical mycology. In 1927, Nan Nizzi reported the description of the sexual state of Microspore gypsum. In 1927, Nannizzi reported the description of the sexual state of Microsporum gypseum the taxonomy of yeast fungi was described by Lodder and Kregervan Rij in 1952. The current classification of dermatophytes was published by Emmons in 1934 Finally, Gentles’ successful treatment of tinea capitis with griseofulvin by in 1958 saved many patients with tinea capitis from permanent hair loss a common side effect after treatment with thallium importance of fungi Fungi inhabit almost every niche in the environment and humans are exposed to these organisms in various fields of life.

Harmful Effects of Fungi:

1. Destruction of food, lumber, paper, and cloth. 2. Animal and human diseases, including allergies . 3. Toxins produced by poisonous mushrooms and within food (Mycelium and Mycotoxicosis) . 4. Plant diseases. 5. Spoilage of agriculture produce such as vegetables and cereals in the godown. 6. Damage the products such as magnetic tapes and disks, glass lenses, marble statues, bones and wax.

Beneficial Effects of Fungi: 1. Decomposition

nutrient and carbon recycling .

2. Biosynthetic factories.

The fermentation property is used for the industrial production of alcohols, fats, citric, oxalic and gluconic acids. 3. Important sources of antibiotics, such as Penicillin.

4. Model organisms for biochemical and genetic studies

. Eg: Neurospora crassa

5. Saccharomyces cerviciae is extensively used in recombinant DNA technology, which includes the Hepatitis B Vaccine

. 6. Some fungi are edible (mushrooms).

7. Yeasts provide nutritional supplements such as vitamins and cofactors.

8. Penicillium is used to flavour Roquefort and Camembert cheeses.

 

Who this course is for:

  • medical students study either medicine pharmacy dentistry veterinary medicine science secondary school prepare themselves to study medicine or become science students prepare themselves to study medicine or science


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